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Gilberto Fronza Selected Research

2,2- bis(hydroxymethyl)- 1- azabicyclo(2,2,2,)octan- 3- one

1/2021Antitumor Effects of PRIMA-1 and PRIMA-1Met (APR246) in Hematological Malignancies: Still a Mutant P53-Dependent Affair?
8/2013PRIMA-1 induces autophagy in cancer cells carrying mutant or wild type p53.
11/2010PRIMA-1 cytotoxicity correlates with nucleolar localization and degradation of mutant p53 in breast cancer cells.

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Gilberto Fronza Research Topics

Disease

16Neoplasms (Cancer)
02/2021 - 08/2003
7B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
10/2022 - 01/2020
3Neuroblastoma
02/2021 - 08/2010
3Neoplasm Metastasis (Metastasis)
02/2021 - 06/2014
2Disease Progression
01/2021 - 10/2020
2Melanoma (Melanoma, Malignant)
10/2017 - 03/2016
1Hematologic Neoplasms (Hematological Malignancy)
01/2021
1Carcinogenesis
04/2014
1Breast Neoplasms (Breast Cancer)
11/2010
1Genomic Instability
07/2010
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
03/2008

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
01/2020 - 01/2011
3MicroRNAs (MicroRNA)IBA
02/2021 - 01/2018
32,2- bis(hydroxymethyl)- 1- azabicyclo(2,2,2,)octan- 3- oneIBA
01/2021 - 11/2010
3DNA (Deoxyribonucleic Acid)IBA
04/2007 - 08/2003
2Rituximab (Mabthera)FDA Link
04/2021 - 01/2021
2ibrutinibIBA
04/2021 - 01/2021
2Protein Isoforms (Isoforms)IBA
03/2020 - 04/2014
2Transcription Factors (Transcription Factor)IBA
10/2017 - 01/2011
2methyl lexitropsinIBA
07/2010 - 03/2008
1Interleukin-23 (Interleukin 23)IBA
10/2022
1serum P-component (CIt)IBA
10/2021
1idelalisibIBA
04/2021
1Bendamustine HydrochlorideFDA Link
01/2021
1Biological ProductsIBA
03/2020
1Biomarkers (Surrogate Marker)IBA
12/2019
1Etoposide (VP 16)FDA LinkGeneric
01/2018
1Oncogene Proteins (Oncogene Protein)IBA
01/2018
1gambogic acidIBA
02/2017
15' Untranslated Regions (5' UTR)IBA
03/2016
1PrionsIBA
06/2014
1Pharmaceutical PreparationsIBA
01/2014
1EnzymesIBA
01/2013
1Proline (L-Proline)FDA Link
01/2013
1Proline Oxidase (Proline Dehydrogenase)IBA
01/2013
1GlutaratesIBA
01/2013
1Glutamic Acid (Glutamate)FDA Link
01/2013
1LuciferasesIBA
01/2011
1Ferritins (Ferritin)IBA
08/2010
1N3-methyladenineIBA
07/2010
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
03/2008
1Peptides (Polypeptides)IBA
08/2006
1Codon (Codons)IBA
08/2003

Therapy/Procedure

7Therapeutics
02/2021 - 02/2004
2Drug Therapy (Chemotherapy)
01/2021 - 10/2020